Set your calendars for October 6, 2024, as the Arizona Cardinals will go head-to-head against the San Francisco 49ers. This anticipated matchup is scheduled for a 4:05 PM kickoff at Levi’s Stadium in Santa Clara.

The Cardinals, holding second place in their division and tenth in their conference, come into this game with a 1-2-0 record and a winning percentage of .333. They have scored a total of 82 points while conceding 64 this season, resulting in a positive net point difference of 18. On the opposing side, the 49ers, positioned fourth in their division and twelfth in their conference, also hold a 1-2-0 record with a matching .333 winning percentage. They have accumulated 73 points but allowed 69, leading to a net point difference of 4.

Quarterback Kyler Murray will be under center for the Cardinals, while Brock Purdy will lead the offense for the 49ers.

Regarding betting odds, the 49ers are the favorites at home with a point spread of -7, suggesting they are expected to win by more than a touchdown. The Cardinals are set with an underdog spread of +7. The total over/under for the game is pegged at 48 points. Direct moneyline bets are also an option, with the 49ers positioned at -345 and the Cardinals at +265. These lines imply a stronger confidence in a 49ers victory, yet each game always has the potential for unpredictability and excitement.